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Direct detection of RNA modifications and structure using single-molecule nanopore sequencing
Modifications are present on many classes of RNA, including tRNA, rRNA, and mRNA. These modifications modulate diverse biological processes such as genetic recoding and mRNA export and folding. In addition, modifications can be introduced to RNA molecules using chemical probing strategies that revea...
Autores principales: | Stephenson, William, Razaghi, Roham, Busan, Steven, Weeks, Kevin M., Timp, Winston, Smibert, Peter |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8896822/ https://www.ncbi.nlm.nih.gov/pubmed/35252946 http://dx.doi.org/10.1016/j.xgen.2022.100097 |
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