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Chondroitin/dermatan sulfate glycosyltransferase genes are essential for craniofacial development

Chondroitin/dermatan sulfate (CS/DS) proteoglycans are indispensable for animal development and homeostasis but the large number of enzymes involved in their biosynthesis have made CS/DS function a challenging problem to study genetically. In our study, we generated loss-of-function alleles in zebra...

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Detalles Bibliográficos
Autores principales: Habicher, Judith, Varshney, Gaurav K., Waldmann, Laura, Snitting, Daniel, Allalou, Amin, Zhang, Hanqing, Ghanem, Abdurrahman, Öhman Mägi, Caroline, Dierker, Tabea, Kjellén, Lena, Burgess, Shawn M., Ledin, Johan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8896900/
https://www.ncbi.nlm.nih.gov/pubmed/35192612
http://dx.doi.org/10.1371/journal.pgen.1010067