Cargando…

IKKβ mediates homeostatic function in inflammation via competitively phosphorylating AMPK and IκBα

Inhibitor of nuclear factor kappa-B kinase subunit beta (IKKβ) is one of important kinases in inflammation to phosphorylate inhibitor of nuclear factor kappa-B (IκBα) and then activate nuclear factor kappa-B (NF-κB). Inhibition of IKKβ has been a therapeutic strategy for inflammatory and autoimmune...

Descripción completa

Detalles Bibliográficos
Autores principales: Liu, Juan, Zhuang, Yuxin, Wu, Jianlin, Wu, Qiang, Liu, Meixian, Zhao, Yue, Liu, Zhongqiu, Wang, Caiyan, Lu, Linlin, Meng, Yingjiao, Lei, Kawai, Li, Xiaojuan, Wu, Qibiao, Leung, Elaine Lai-Han, Guo, Zhengyang, Liu, Liang, Li, Ting
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8897026/
https://www.ncbi.nlm.nih.gov/pubmed/35256937
http://dx.doi.org/10.1016/j.apsb.2021.09.012