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IKKβ mediates homeostatic function in inflammation via competitively phosphorylating AMPK and IκBα
Inhibitor of nuclear factor kappa-B kinase subunit beta (IKKβ) is one of important kinases in inflammation to phosphorylate inhibitor of nuclear factor kappa-B (IκBα) and then activate nuclear factor kappa-B (NF-κB). Inhibition of IKKβ has been a therapeutic strategy for inflammatory and autoimmune...
Autores principales: | Liu, Juan, Zhuang, Yuxin, Wu, Jianlin, Wu, Qiang, Liu, Meixian, Zhao, Yue, Liu, Zhongqiu, Wang, Caiyan, Lu, Linlin, Meng, Yingjiao, Lei, Kawai, Li, Xiaojuan, Wu, Qibiao, Leung, Elaine Lai-Han, Guo, Zhengyang, Liu, Liang, Li, Ting |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8897026/ https://www.ncbi.nlm.nih.gov/pubmed/35256937 http://dx.doi.org/10.1016/j.apsb.2021.09.012 |
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