Inhibition of temperature-sensitive TRPV3 channel by two natural isochlorogenic acid isomers for alleviation of dermatitis and chronic pruritus

Genetic gain-of-function mutations of warm temperature-sensitive transient receptor potential vanilloid 3 (TRPV3) channel cause Olmsted syndrome characterized by severe itching and keratoderma, indicating that pharmacological inhibition of TRPV3 may hold promise for therapy of chronic pruritus and s...

Descripción completa

Detalles Bibliográficos
Autores principales: Qi, Hang, Shi, Yuntao, Wu, Han, Niu, Canyang, Sun, Xiaoying, Wang, KeWei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Short Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8897028/
https://www.ncbi.nlm.nih.gov/pubmed/35256942
http://dx.doi.org/10.1016/j.apsb.2021.08.002

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8897028/
https://www.ncbi.nlm.nih.gov/pubmed/35256942
http://dx.doi.org/10.1016/j.apsb.2021.08.002

Ejemplares similares