Cargando…

Preclinical evaluation and pilot clinical study of [(18)F]AlF-labeled FAPI-tracer for PET imaging of cancer associated fibroblasts

In recent years, fibroblast activation protein (FAP) has emerged as an attractive target for the diagnosis and radiotherapy of cancers using FAP-specific radioligands. Herein, we aimed to design a novel (18)F-labeled FAP tracer ([(18)F]AlF-P-FAPI) for FAP imaging and evaluated its potential for clin...

Descripción completa

Detalles Bibliográficos
Autores principales: Hu, Kongzhen, Li, Junqi, Wang, Lijuan, Huang, Yong, Li, Li, Ye, Shimin, Han, Yanjiang, Huang, Shun, Wu, Hubing, Su, Jin, Tang, Ganghua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8897030/
https://www.ncbi.nlm.nih.gov/pubmed/35256951
http://dx.doi.org/10.1016/j.apsb.2021.09.032