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Preclinical evaluation and pilot clinical study of [(18)F]AlF-labeled FAPI-tracer for PET imaging of cancer associated fibroblasts
In recent years, fibroblast activation protein (FAP) has emerged as an attractive target for the diagnosis and radiotherapy of cancers using FAP-specific radioligands. Herein, we aimed to design a novel (18)F-labeled FAP tracer ([(18)F]AlF-P-FAPI) for FAP imaging and evaluated its potential for clin...
Autores principales: | Hu, Kongzhen, Li, Junqi, Wang, Lijuan, Huang, Yong, Li, Li, Ye, Shimin, Han, Yanjiang, Huang, Shun, Wu, Hubing, Su, Jin, Tang, Ganghua |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8897030/ https://www.ncbi.nlm.nih.gov/pubmed/35256951 http://dx.doi.org/10.1016/j.apsb.2021.09.032 |
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