Anti-aging effects of chlorpropamide depend on mitochondrial complex-II and the production of mitochondrial reactive oxygen species

Sulfonylureas are widely used oral anti-diabetic drugs. However, its long-term usage effects on patients’ lifespan remain controversial, with no reports of influence on animal longevity. Hence, the anti-aging effects of chlorpropamide along with glimepiride, glibenclamide, and tolbutamide were studi...

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Detalles Bibliográficos
Autores principales: Mao, Zhifan, Liu, Wenwen, Huang, Yunyuan, Sun, Tianyue, Bao, Keting, Feng, Jiali, Moskalev, Alexey, Hu, Zelan, Li, Jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8897034/
https://www.ncbi.nlm.nih.gov/pubmed/35256938
http://dx.doi.org/10.1016/j.apsb.2021.08.007

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8897034/
https://www.ncbi.nlm.nih.gov/pubmed/35256938
http://dx.doi.org/10.1016/j.apsb.2021.08.007

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