Aging-elevated inflammation promotes DNMT3A R878H-driven clonal hematopoiesis

Aging-elevated DNMT3A R882H-driven clonal hematopoiesis (CH) is a risk factor for myeloid malignancies remission and overall survival. Although some studies were conducted to investigate this phenomenon, the exact mechanism is still under debate. In this study, we observed that DNMT3A R878H bone mar...

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Detalles Bibliográficos
Autores principales: Liao, Min, Chen, Ruiqing, Yang, Yang, He, Hanqing, Xu, Liqian, Jiang, Yuxuan, Guo, Zhenxing, He, Wei, Jiang, Hong, Wang, Jianwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8897035/
https://www.ncbi.nlm.nih.gov/pubmed/35256939
http://dx.doi.org/10.1016/j.apsb.2021.09.015

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8897035/
https://www.ncbi.nlm.nih.gov/pubmed/35256939
http://dx.doi.org/10.1016/j.apsb.2021.09.015

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