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Aging-elevated inflammation promotes DNMT3A R878H-driven clonal hematopoiesis
Aging-elevated DNMT3A R882H-driven clonal hematopoiesis (CH) is a risk factor for myeloid malignancies remission and overall survival. Although some studies were conducted to investigate this phenomenon, the exact mechanism is still under debate. In this study, we observed that DNMT3A R878H bone mar...
| Autores principales: | , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8897035/ https://www.ncbi.nlm.nih.gov/pubmed/35256939 http://dx.doi.org/10.1016/j.apsb.2021.09.015 |