Cargando…

TGR5 deficiency activates antitumor immunity in non-small cell lung cancer via restraining M2 macrophage polarization

The bile acid-responsive G-protein-coupled receptor TGR5 is expressed in monocytes and macrophages, and plays a critical role in regulating inflammatory response. Our previous work has shown its role in promoting the progression of non-small cell lung cancer (NSCLC), yet the mechanism remains unclea...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhao, Lifang, Zhang, Hongyan, Liu, Xueqing, Xue, Shan, Chen, Dongfang, Zou, Jing, Jiang, Handong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8897042/
https://www.ncbi.nlm.nih.gov/pubmed/35256947
http://dx.doi.org/10.1016/j.apsb.2021.07.011