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TGR5 deficiency activates antitumor immunity in non-small cell lung cancer via restraining M2 macrophage polarization
The bile acid-responsive G-protein-coupled receptor TGR5 is expressed in monocytes and macrophages, and plays a critical role in regulating inflammatory response. Our previous work has shown its role in promoting the progression of non-small cell lung cancer (NSCLC), yet the mechanism remains unclea...
Autores principales: | Zhao, Lifang, Zhang, Hongyan, Liu, Xueqing, Xue, Shan, Chen, Dongfang, Zou, Jing, Jiang, Handong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8897042/ https://www.ncbi.nlm.nih.gov/pubmed/35256947 http://dx.doi.org/10.1016/j.apsb.2021.07.011 |
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