Apolipoprotein E and Alzheimer's disease

Genetic variation in apolipoprotein E (APOE) influences Alzheimer's disease (AD) risk. APOE ε4 alleles are the strongest genetic risk factor for late onset sporadic AD. The AD risk is dose dependent, as those carrying one APOE ε4 allele have a 2–3-fold increased risk, while those carrying two ε...

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Detalles Bibliográficos
Autores principales: Troutwine, Benjamin R., Hamid, Laylan, Lysaker, Colton R., Strope, Taylor A., Wilkins, Heather M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8897057/
https://www.ncbi.nlm.nih.gov/pubmed/35256931
http://dx.doi.org/10.1016/j.apsb.2021.10.002

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8897057/
https://www.ncbi.nlm.nih.gov/pubmed/35256931
http://dx.doi.org/10.1016/j.apsb.2021.10.002

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