Cargando…

Apolipoprotein E and Alzheimer's disease

Genetic variation in apolipoprotein E (APOE) influences Alzheimer's disease (AD) risk. APOE ε4 alleles are the strongest genetic risk factor for late onset sporadic AD. The AD risk is dose dependent, as those carrying one APOE ε4 allele have a 2–3-fold increased risk, while those carrying two ε...

Descripción completa

Detalles Bibliográficos
Autores principales:	Troutwine, Benjamin R., Hamid, Laylan, Lysaker, Colton R., Strope, Taylor A., Wilkins, Heather M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2022
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8897057/ https://www.ncbi.nlm.nih.gov/pubmed/35256931 http://dx.doi.org/10.1016/j.apsb.2021.10.002

Ejemplares similares

Cell type and sex specific mitochondrial phenotypes in iPSC derived models of Alzheimer’s disease
por: Flannagan, Kaitlin, et al.
Publicado: (2023)

Therapeutic approaches targeting Apolipoprotein E function in Alzheimer’s disease
por: Williams, Tosha, et al.
Publicado: (2020)

Function and Comorbidities of Apolipoprotein E in Alzheimer's Disease
por: Leduc, Valérie, et al.
Publicado: (2011)

Targeting Apolipoprotein E for Alzheimer’s Disease: An Industry Perspective
por: Suidan, Georgette L., et al.
Publicado: (2019)

Apolipoprotein E4, inhibitory network dysfunction, and Alzheimer’s disease
por: Najm, Ramsey, et al.
Publicado: (2019)

The Role of Bioenergetics in Neurodegeneration
por: Strope, Taylor A., et al.
Publicado: (2022)

Apolipoprotein A1, the neglected relative of Apolipoprotein E and its potential role in Alzheimer’s disease
por: Endres, Kristina
Publicado: (2021)

Apolipoprotein E and Alzheimer's disease: molecular mechanisms and therapeutic opportunities
por: Cedazo-Mínguez, Angel
Publicado: (2007)

Interactions of metals and Apolipoprotein E in Alzheimer’s disease
por: Xu, He, et al.
Publicado: (2014)

Apolipoprotein E as a β-amyloid-independent factor in Alzheimer’s disease
por: Wolf, Andrew B, et al.
Publicado: (2013)

Apolipoprotein E, amyloid-ß clearance and therapeutic opportunities in Alzheimer's disease
por: Kline, Adam
Publicado: (2012)

Association between Alzheimer’s Disease and Apolipoprotein E Polymorphisms
por: Gozalpour, E, et al.
Publicado: (2010)

Bibliometric analysis of global research on the role of apolipoprotein E in Alzheimer's disease
por: Wang, Zhanzhang, et al.
Publicado: (2023)

Apolipoprotein E region molecular signatures of Alzheimer's disease
por: Kulminski, Alexander M., et al.
Publicado: (2018)

Are apolipoprotein E fragments a promising new therapeutic target for Alzheimer’s disease?
por: Vecchio, Filomena Lo, et al.
Publicado: (2022)

Apolipoprotein E ε-4 as a genetic determinant of Alzheimer’s disease heterogeneity
por: Kotze, MJ, et al.
Publicado: (2015)

Apolipoprotein E: Essential Catalyst of the Alzheimer Amyloid Cascade
por: Potter, Huntington, et al.
Publicado: (2012)

Apolipoprotein E4 and meningeal lymphatics in Alzheimer disease: a conceptual framework
por: Mentis, Alexios-Fotios A., et al.
Publicado: (2020)

Apolipoprotein E particle size is increased in Alzheimer's disease
por: Nelson, Thomas J., et al.
Publicado: (2018)

The Important Interface Between Apolipoprotein E and Neuroinflammation in Alzheimer’s Disease
por: Kloske, Courtney M., et al.
Publicado: (2020)

Effect of apolipoprotein E (APO E) polymorphism on leptin in Alzheimer's disease
por: Agarwal, Rachna, et al.
Publicado: (2015)

Proteolytic Cleavage of Apolipoprotein E4 as the Keystone for the Heightened Risk Associated with Alzheimer’s Disease
por: Rohn, Troy T.
Publicado: (2013)

Impact of apolipoprotein E isoforms on sporadic Alzheimer’s disease: beyond the role of amyloid beta
por: Lozupone, Madia, et al.
Publicado: (2023)

The influence of Apolipoprotein E genotype on regional pathology in Alzheimer’s disease
por: Sabbagh, Marwan N, et al.
Publicado: (2013)

Role of apolipoprotein E in neurodegenerative diseases
por: Giau, Vo Van, et al.
Publicado: (2015)

Apolipoprotein E imbalance in the cerebrospinal fluid of Alzheimer’s disease patients
por: Lennol, Matthew Paul, et al.
Publicado: (2022)

Diagnosis Test Meta-Analysis for Apolipoprotein E in Alzheimer's Disease
por: Xiong, Xuan, et al.
Publicado: (2020)

Apolipoprotein E e4 allele is associated with extrapyramidal symptoms in Alzheimer’s disease
por: Chang, Yang-Pei, et al.
Publicado: (2019)

Meta-Analysis of Peripheral Blood Apolipoprotein E Levels in Alzheimer’s Disease
por: Wang, Chong, et al.
Publicado: (2014)

Apolipoprotein E metabolism and functions in brain and its role in Alzheimer's disease
por: Liao, Fan, et al.
Publicado: (2017)

Aggregate Trends of Apolipoprotein E on Cognition in Transgenic Alzheimer’s Disease Mice
por: Watson, Yassin, et al.
Publicado: (2021)

Investigation of the Relationship between Apolipoprotein E Alleles and Serum Lipids in Alzheimer’s Disease: A Meta-Analysis
por: Xu, Huaxue, et al.
Publicado: (2023)

Impact of apolipoprotein E genotypes on vitamin E and memantine treatment outcomes in Alzheimer's disease
por: Belitskaya-Lévy, Ilana, et al.
Publicado: (2018)

Apolipoprotein E ɛ4–related effects on cognition are limited to the Alzheimer’s disease spectrum
por: Fernández, Alberto, et al.
Publicado: (2021)

Apolipoprotein E in Cardiometabolic and Neurological Health and Diseases
por: Alagarsamy, Jeyashree, et al.
Publicado: (2022)

Alzheimer Disease: Recent Updates on Apolipoprotein E and Gut Microbiome Mediation of Oxidative Stress, and Prospective Interventional Agents
por: Botchway, Benson OA, et al.
Publicado: (2022)

Apolipoproteins and Alzheimer's pathophysiology
por: Koch, Manja, et al.
Publicado: (2018)

The blood-brain barrier models to study apolipoprotein E genotypes in Alzheimer's disease
por: Dias, Irundika HK, et al.
Publicado: (2022)

Apolipoprotein E in Synaptic Plasticity and Alzheimer’s Disease: Potential Cellular and Molecular Mechanisms
por: Kim, Jaekwang, et al.
Publicado: (2014)

Clusterin accumulates in synapses in Alzheimer’s disease and is increased in apolipoprotein E4 carriers
por: Jackson, Rosemary J, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_llio7q8g7pok23be6qvg3imefn