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Mitochondrial complex I as a therapeutic target for Alzheimer's disease

Alzheimer's disease (AD), the most prominent form of dementia in the elderly, has no cure. Strategies focused on the reduction of amyloid beta or hyperphosphorylated Tau protein have largely failed in clinical trials. Novel therapeutic targets and strategies are urgently needed. Emerging data s...

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Detalles Bibliográficos
Autores principales: Trushina, Eugenia, Trushin, Sergey, Hasan, Md Fayad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8897152/
https://www.ncbi.nlm.nih.gov/pubmed/35256930
http://dx.doi.org/10.1016/j.apsb.2021.11.003