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A novel PI3K inhibitor XH30 suppresses orthotopic glioblastoma and brain metastasis in mice models
Glioblastoma is carcinogenesis of glial cells in central nervous system and has the highest incidence among primary brain tumors. Brain metastasis, such as breast cancer and lung cancer, also leads to high mortality. The available medicines are limited due to blood–brain barrier. Abnormal activation...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8897175/ https://www.ncbi.nlm.nih.gov/pubmed/35256946 http://dx.doi.org/10.1016/j.apsb.2021.05.019 |