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A novel PI3K inhibitor XH30 suppresses orthotopic glioblastoma and brain metastasis in mice models

Glioblastoma is carcinogenesis of glial cells in central nervous system and has the highest incidence among primary brain tumors. Brain metastasis, such as breast cancer and lung cancer, also leads to high mortality. The available medicines are limited due to blood–brain barrier. Abnormal activation...

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Detalles Bibliográficos
Autores principales:	Ji, Ming, Wang, Dongjie, Lin, Songwen, Wang, Chunyang, Li, Ling, Zhang, Zhihui, Jin, Jing, Wu, Deyu, Dong, Yi, Xu, Heng, Lu, Duo, Chen, Xiaoguang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2022
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8897175/ https://www.ncbi.nlm.nih.gov/pubmed/35256946 http://dx.doi.org/10.1016/j.apsb.2021.05.019

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