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Genomic instability induced by radiation-mimicking chemicals is not associated with persistent mitochondrial degeneration

Ionizing radiation has been shown to cause induced genomic instability (IGI), which is defined as a persistently increased rate of genomic damage in the progeny of the exposed cells. In this study, IGI was investigated by exposing human SH-SY5Y neuroblastoma cells to hydroxyurea and zeocin, two chem...

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Detalles Bibliográficos
Autores principales: Luukkonen, Jukka, Höytö, Anne, Sokka, Miiko, Syväoja, Juhani, Juutilainen, Jukka, Naarala, Jonne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8897345/
https://www.ncbi.nlm.nih.gov/pubmed/34331120
http://dx.doi.org/10.1007/s00411-021-00927-5