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Effects of oligomer toxicity, fibril toxicity and fibril spreading in synucleinopathies

Protein misfolding is a general hallmark of protein deposition diseases, such as Alzheimer’s disease or Parkinson’s disease, in which different types of aggregated species (oligomers, protofibrils and fibrils) are generated by the cells. Despite widespread interest, the relationship between oligomer...

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Detalles Bibliográficos
Autores principales: Cascella, Roberta, Bigi, Alessandra, Cremades, Nunilo, Cecchi, Cristina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8897347/
https://www.ncbi.nlm.nih.gov/pubmed/35244787
http://dx.doi.org/10.1007/s00018-022-04166-9