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Effects of oligomer toxicity, fibril toxicity and fibril spreading in synucleinopathies
Protein misfolding is a general hallmark of protein deposition diseases, such as Alzheimer’s disease or Parkinson’s disease, in which different types of aggregated species (oligomers, protofibrils and fibrils) are generated by the cells. Despite widespread interest, the relationship between oligomer...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer International Publishing
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8897347/ https://www.ncbi.nlm.nih.gov/pubmed/35244787 http://dx.doi.org/10.1007/s00018-022-04166-9 |