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Enhanced pro-apoptosis gene signature following the activation of TAp63α in oocytes upon γ irradiation

Specialized surveillance mechanisms are essential to maintain the genetic integrity of germ cells, which are not only the source of all somatic cells but also of the germ cells of the next generation. DNA damage and chromosomal aberrations are, therefore, not only detrimental for the individual but...

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Detalles Bibliográficos
Autores principales: Fester, Niclas, Zielonka, Elisabeth, Goldmann, Jakob, Frombach, Ann-Sophie, Müller-Kuller, Uta, Gutfreund, Niklas, Riegel, Kristina, Smits, Jos G. A., Schleiff, Enrico, Rajalingam, Krishnaraj, Zhou, Huiqing, Simm, Stefan, Dötsch, Volker
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8897389/
https://www.ncbi.nlm.nih.gov/pubmed/35246516
http://dx.doi.org/10.1038/s41419-022-04659-2