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Zeb1-induced metabolic reprogramming of glycolysis is essential for macrophage polarization in breast cancer

Aerobic glycolysis (the Warburg effect) has been demonstrated to facilitate tumor progression by producing lactate, which has important roles as a proinflammatory and immunosuppressive mediator. However, how aerobic glycolysis is directly regulated is largely unknown. Here, we show that ectopic Zeb1...

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Detalles Bibliográficos
Autores principales: Jiang, Huimin, Wei, Huimin, Wang, Hang, Wang, Zhaoyang, Li, Jianjun, Ou, Yang, Xiao, Xuechun, Wang, Wenhao, Chang, Antao, Sun, Wei, Zhao, Li, Yang, Shuang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8897397/
https://www.ncbi.nlm.nih.gov/pubmed/35246504
http://dx.doi.org/10.1038/s41419-022-04632-z