In vitro maturation of Toxoplasma gondii bradyzoites in human myotubes and their metabolomic characterization

The apicomplexan parasite Toxoplasma gondii forms bradyzoite-containing tissue cysts that cause chronic and drug-tolerant infections. However, current in vitro models do not allow long-term culture of these cysts to maturity. Here, we developed a human myotube-based in vitro culture model of functio...

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Detalles Bibliográficos
Autores principales: Christiansen, Céline, Maus, Deborah, Hoppenz, Ellen, Murillo-León, Mateo, Hoffmann, Tobias, Scholz, Jana, Melerowicz, Florian, Steinfeldt, Tobias, Seeber, Frank, Blume, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8897399/
https://www.ncbi.nlm.nih.gov/pubmed/35246532
http://dx.doi.org/10.1038/s41467-022-28730-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8897399/
https://www.ncbi.nlm.nih.gov/pubmed/35246532
http://dx.doi.org/10.1038/s41467-022-28730-w

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