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In vitro maturation of Toxoplasma gondii bradyzoites in human myotubes and their metabolomic characterization
The apicomplexan parasite Toxoplasma gondii forms bradyzoite-containing tissue cysts that cause chronic and drug-tolerant infections. However, current in vitro models do not allow long-term culture of these cysts to maturity. Here, we developed a human myotube-based in vitro culture model of functio...
Autores principales: | Christiansen, Céline, Maus, Deborah, Hoppenz, Ellen, Murillo-León, Mateo, Hoffmann, Tobias, Scholz, Jana, Melerowicz, Florian, Steinfeldt, Tobias, Seeber, Frank, Blume, Martin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8897399/ https://www.ncbi.nlm.nih.gov/pubmed/35246532 http://dx.doi.org/10.1038/s41467-022-28730-w |
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