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Human infrapatellar fat pad mesenchymal stem cells show immunomodulatory exosomal signatures

Within the human knee infrapatellar fat pad (IFP) and synovium, resident synoviocytes and macrophages contribute to the onset and progression of inflammatory joint diseases. Our hypothesis is that IFP-derived mesenchymal stem cells (IFP-MSC) robust immunomodulatory therapeutic effects are largely ex...

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Detalles Bibliográficos
Autores principales: Kouroupis, Dimitrios, Kaplan, Lee D., Best, Thomas M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8897449/
https://www.ncbi.nlm.nih.gov/pubmed/35246587
http://dx.doi.org/10.1038/s41598-022-07569-7