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Leptin secreted from testicular microenvironment modulates hedgehog signaling to augment the endogenous function of Leydig cells
Although testosterone deficiency (TD) may be present in one out of five men 40 years or older, the factors responsible for TD remain largely unknown. Leydig stem cells (LSCs) differentiate into adult Leydig cells (ALC) and produce testosterone in the testes under the pulsatile control of luteinizing...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8897450/ https://www.ncbi.nlm.nih.gov/pubmed/35246515 http://dx.doi.org/10.1038/s41419-022-04658-3 |