Leptin secreted from testicular microenvironment modulates hedgehog signaling to augment the endogenous function of Leydig cells

Although testosterone deficiency (TD) may be present in one out of five men 40 years or older, the factors responsible for TD remain largely unknown. Leydig stem cells (LSCs) differentiate into adult Leydig cells (ALC) and produce testosterone in the testes under the pulsatile control of luteinizing...

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Detalles Bibliográficos
Autores principales: Arora, Himanshu, Qureshi, Rehana, Khodamoradi, Kajal, Seetharam, Deepa, Parmar, Madhumita, Van Booven, Derek J., Issa, Isabelle Catherine, Sackstein, Robert, Lamb, Dolores, Hare, Joshua M., Ramasamy, Ranjith
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8897450/
https://www.ncbi.nlm.nih.gov/pubmed/35246515
http://dx.doi.org/10.1038/s41419-022-04658-3

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