Metabolomics and biochemical alterations caused by pleiotrophin in the 6-hydroxydopamine mouse model of Parkinson’s disease

Pleiotrophin (PTN) is a cytokine involved in nerve tissue repair processes, neuroinflammation and neuronal survival. PTN expression levels are upregulated in the nigrostriatal pathway of Parkinson’s Disease (PD) patients. We aimed to characterize the dopaminergic injury and glial responses in the ni...

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Detalles Bibliográficos
Autores principales: Gramage, Esther, Sáiz, Jorge, Fernández-Calle, Rosalía, Martín, Yasmina B., Uribarri, María, Ferrer-Alcón, Marcel, Barbas, Coral, Herradón, Gonzalo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8897456/
https://www.ncbi.nlm.nih.gov/pubmed/35246557
http://dx.doi.org/10.1038/s41598-022-07419-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8897456/
https://www.ncbi.nlm.nih.gov/pubmed/35246557
http://dx.doi.org/10.1038/s41598-022-07419-6

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