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White matter integrity in mice requires continuous myelin synthesis at the inner tongue

Myelin, the electrically insulating sheath on axons, undergoes dynamic changes over time. However, it is composed of proteins with long lifetimes. This raises the question how such a stable structure is renewed. Here, we study the integrity of myelinated tracts after experimentally preventing the fo...

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Detalles Bibliográficos
Autores principales: Meschkat, Martin, Steyer, Anna M., Weil, Marie-Theres, Kusch, Kathrin, Jahn, Olaf, Piepkorn, Lars, Agüi-Gonzalez, Paola, Phan, Nhu Thi Ngoc, Ruhwedel, Torben, Sadowski, Boguslawa, Rizzoli, Silvio O., Werner, Hauke B., Ehrenreich, Hannelore, Nave, Klaus-Armin, Möbius, Wiebke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8897471/
https://www.ncbi.nlm.nih.gov/pubmed/35246535
http://dx.doi.org/10.1038/s41467-022-28720-y