Extrachromosomal DNA formation enables tumor immune escape potentially through regulating antigen presentation gene expression

Extrachromosomal DNA (ecDNA) is a type of circular and tumor specific genetic element. EcDNA has been reported to display open chromatin structure, facilitate oncogene amplification and genetic material unequal segregation, and is associated with poor cancer patients’ prognosis. The ability of immun...

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Detalles Bibliográficos
Autores principales: Wu, Tao, Wu, Chenxu, Zhao, Xiangyu, Wang, Guangshuai, Ning, Wei, Tao, Ziyu, Chen, Fuxiang, Liu, Xue-Song
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8897507/
https://www.ncbi.nlm.nih.gov/pubmed/35246593
http://dx.doi.org/10.1038/s41598-022-07530-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8897507/
https://www.ncbi.nlm.nih.gov/pubmed/35246593
http://dx.doi.org/10.1038/s41598-022-07530-8

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