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Extrachromosomal DNA formation enables tumor immune escape potentially through regulating antigen presentation gene expression
Extrachromosomal DNA (ecDNA) is a type of circular and tumor specific genetic element. EcDNA has been reported to display open chromatin structure, facilitate oncogene amplification and genetic material unequal segregation, and is associated with poor cancer patients’ prognosis. The ability of immun...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8897507/ https://www.ncbi.nlm.nih.gov/pubmed/35246593 http://dx.doi.org/10.1038/s41598-022-07530-8 |