T cell receptors employ diverse strategies to target a p53 cancer neoantigen

Adoptive cell therapy with tumor-specific T cells can mediate durable cancer regression. The prime target of tumor-specific T cells are neoantigens arising from mutations in self-proteins during malignant transformation. To understand T cell recognition of cancer neoantigens at the atomic level, we...

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Detalles Bibliográficos
Autores principales: Wu, Daichao, Gowathaman, Ragul, Pierce, Brian G., Mariuzza, Roy A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8897694/
https://www.ncbi.nlm.nih.gov/pubmed/35124005
http://dx.doi.org/10.1016/j.jbc.2022.101684

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8897694/
https://www.ncbi.nlm.nih.gov/pubmed/35124005
http://dx.doi.org/10.1016/j.jbc.2022.101684

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