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RUNX1 inhibits the antiviral immune response against influenza A virus through attenuating type I interferon signaling

BACKGROUND: Influenza A viruses (IAVs) are zoonotic, segmented negative-stranded RNA viruses. The rapid mutation of IAVs results in host immune response escape and antiviral drug and vaccine resistance. RUNX1 is a transcription factor that not only plays essential roles in hematopoiesis, but also fu...

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Detalles Bibliográficos
Autores principales: Hu, Yixiang, Pan, Qi, Zhou, Kun, Ling, Yuehuan, Wang, Hao, Li, Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8897766/
https://www.ncbi.nlm.nih.gov/pubmed/35248104
http://dx.doi.org/10.1186/s12985-022-01764-8