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RUNX1 inhibits the antiviral immune response against influenza A virus through attenuating type I interferon signaling
BACKGROUND: Influenza A viruses (IAVs) are zoonotic, segmented negative-stranded RNA viruses. The rapid mutation of IAVs results in host immune response escape and antiviral drug and vaccine resistance. RUNX1 is a transcription factor that not only plays essential roles in hematopoiesis, but also fu...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8897766/ https://www.ncbi.nlm.nih.gov/pubmed/35248104 http://dx.doi.org/10.1186/s12985-022-01764-8 |