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Integrin β3 in forebrain Emx1-expressing cells regulates repetitive self-grooming and sociability in mice

BACKGROUND: Autism spectrum disorder (ASD) is characterized by repetitive behaviors, deficits in communication, and overall impaired social interaction. Of all the integrin subunit mutations, mutations in integrin β3 (Itgb3) may be the most closely associated with ASD. Integrin β3 is required for no...

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Detalles Bibliográficos
Autores principales: Lopuch, Andrew J., Swinehart, Brian D., Widener, Eden L., Holley, Z. Logan, Bland, Katherine M., Handwerk, Christopher J., Brett, Cooper A., Cook, Hollyn N., Kalinowski, Anna R., Rodriguez, Hilda V., Song, M. Irene, Vidal, George S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8897866/
https://www.ncbi.nlm.nih.gov/pubmed/35247972
http://dx.doi.org/10.1186/s12868-022-00691-2