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Lung damage created by high tidal volume ventilation in rats with monocrotaline-induced pulmonary hypertension

BACKGROUND: Rats with chronic hypoxia-induced non-inflammatory pulmonary hypertension (PH) are resistant to ventilator-induced lung injury. We investigated the effect of high tidal volume ventilation in another model of PH, monocrotaline (MCT)-induced PH, which is a type of inflammatory PH. METHODS:...

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Detalles Bibliográficos
Autores principales: Kawai, Masako, Zhang, Erquan, Kabwe, Jane Chanda, Okada, Amphone, Maruyama, Junko, Sawada, Hirofumi, Maruyama, Kazuo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8897872/
https://www.ncbi.nlm.nih.gov/pubmed/35247989
http://dx.doi.org/10.1186/s12890-022-01867-6