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Changes in DNA methylation hallmark alterations in chromatin accessibility and gene expression for eye lens differentiation

BACKGROUND: Methylation at cytosines (mCG) is a well-known regulator of gene expression, but its requirements for cellular differentiation have yet to be fully elucidated. A well-studied cellular differentiation model system is the eye lens, consisting of a single anterior layer of epithelial cells...

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Detalles Bibliográficos
Autores principales: Disatham, Joshua, Brennan, Lisa, Jiao, Xiaodong, Ma, Zhiwei, Hejtmancik, J. Fielding, Kantorow, Marc
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8897925/
https://www.ncbi.nlm.nih.gov/pubmed/35246225
http://dx.doi.org/10.1186/s13072-022-00440-z