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Changes in DNA methylation hallmark alterations in chromatin accessibility and gene expression for eye lens differentiation
BACKGROUND: Methylation at cytosines (mCG) is a well-known regulator of gene expression, but its requirements for cellular differentiation have yet to be fully elucidated. A well-studied cellular differentiation model system is the eye lens, consisting of a single anterior layer of epithelial cells...
Autores principales: | Disatham, Joshua, Brennan, Lisa, Jiao, Xiaodong, Ma, Zhiwei, Hejtmancik, J. Fielding, Kantorow, Marc |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8897925/ https://www.ncbi.nlm.nih.gov/pubmed/35246225 http://dx.doi.org/10.1186/s13072-022-00440-z |
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