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Let-7a Targeting TNFAPI3 Promotes Vascular Endothelial Cell Apoptosis of Pediatric Patients with Henoch–Schönlein Purpura via NF-κB Signaling Pathway

OBJECTIVE: We aimed at exploring the role of let-7a in the pathogenesis of pediatric Henoch–Schönlein purpura (HSP) and its related mechanism. METHODS: Fifty-five pediatric HSP patients and 20 paired healthy controls were included. The expressions of let-7a and TNFAIP3 were detected by RT-qPCR or/an...

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Detalles Bibliográficos
Autores principales: Cui, Mingming, Liu, Jilong, Geng, Li, Li, Qianqian, Xi, Leiming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8898105/
https://www.ncbi.nlm.nih.gov/pubmed/35256897
http://dx.doi.org/10.1155/2022/3889318