Cargando…

Met–HER3 crosstalk supports proliferation via MPZL3 in MET-amplified cancer cells

Receptor tyrosine kinases (RTKs) are recognized as targets of precision medicine in human cancer upon their gene amplification or constitutive activation, resulting in increased downstream signal complexity including heterotypic crosstalk with other RTKs. The Met RTK exhibits such reciprocal crossta...

Descripción completa

Detalles Bibliográficos
Autores principales: Stern, Yaakov E., Al-Ghabkari, Abdulhameed, Monast, Anie, Fiset, Benoit, Aboualizadeh, Farzaneh, Yao, Zhong, Stagljar, Igor, Walsh, Logan A., Duhamel, Stephanie, Park, Morag
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8898245/
https://www.ncbi.nlm.nih.gov/pubmed/35249128
http://dx.doi.org/10.1007/s00018-022-04149-w