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Quantification of T- and B-cell Immune Receptor Distribution Diversity Characterizes Immune Cell Infiltration and Lymphocyte Heterogeneity in Clear Cell Renal Cell Carcinoma

Immune-modulating systemic therapies are often used to treat advanced cancer such as metastatic clear cell renal cell carcinoma (ccRCC). Used alone, sequence-based biomarkers neither accurately capture patient dynamics nor the tumor immune microenvironment. To better understand the tumor ecology of...

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Detalles Bibliográficos
Autores principales: Ferrall-Fairbanks, Meghan C., Chakiryan, Nicholas H., Chobrutskiy, Boris I., Kim, Youngchul, Teer, Jamie K., Berglund, Anders, Mulé, James J., Fournier, Michelle, Siegel, Erin M., Dhillon, Jasreman, Falasiri, Seyed Shayan A., Arturo, Juan F., Katende, Esther N., Blanck, George, Manley, Brandon J., Altrock, Philipp M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for Cancer Research 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8898280/
https://www.ncbi.nlm.nih.gov/pubmed/35031572
http://dx.doi.org/10.1158/0008-5472.CAN-21-1747