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Quantification of T- and B-cell Immune Receptor Distribution Diversity Characterizes Immune Cell Infiltration and Lymphocyte Heterogeneity in Clear Cell Renal Cell Carcinoma
Immune-modulating systemic therapies are often used to treat advanced cancer such as metastatic clear cell renal cell carcinoma (ccRCC). Used alone, sequence-based biomarkers neither accurately capture patient dynamics nor the tumor immune microenvironment. To better understand the tumor ecology of...
Autores principales: | Ferrall-Fairbanks, Meghan C., Chakiryan, Nicholas H., Chobrutskiy, Boris I., Kim, Youngchul, Teer, Jamie K., Berglund, Anders, Mulé, James J., Fournier, Michelle, Siegel, Erin M., Dhillon, Jasreman, Falasiri, Seyed Shayan A., Arturo, Juan F., Katende, Esther N., Blanck, George, Manley, Brandon J., Altrock, Philipp M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Association for Cancer Research
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8898280/ https://www.ncbi.nlm.nih.gov/pubmed/35031572 http://dx.doi.org/10.1158/0008-5472.CAN-21-1747 |
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