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Mechanical Stress Signaling in Pancreatic Cancer Cells Triggers p38 MAPK- and JNK-Dependent Cytoskeleton Remodeling and Promotes Cell Migration via Rac1/cdc42/Myosin II

Advanced or metastatic pancreatic cancer is highly resistant to existing therapies, and new treatments are urgently needed to improve patient outcomes. Current studies focus on alternative treatment approaches that target the abnormal microenvironment of pancreatic tumors and the resulting elevated...

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Detalles Bibliográficos
Autores principales: Kalli, Maria, Li, Ruxuan, Mills, Gordon B., Stylianopoulos, Triantafyllos, Zervantonakis, Ioannis K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for Cancer Research 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8898300/
https://www.ncbi.nlm.nih.gov/pubmed/34782370
http://dx.doi.org/10.1158/1541-7786.MCR-21-0266