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Mechanical Stress Signaling in Pancreatic Cancer Cells Triggers p38 MAPK- and JNK-Dependent Cytoskeleton Remodeling and Promotes Cell Migration via Rac1/cdc42/Myosin II
Advanced or metastatic pancreatic cancer is highly resistant to existing therapies, and new treatments are urgently needed to improve patient outcomes. Current studies focus on alternative treatment approaches that target the abnormal microenvironment of pancreatic tumors and the resulting elevated...
Autores principales: | Kalli, Maria, Li, Ruxuan, Mills, Gordon B., Stylianopoulos, Triantafyllos, Zervantonakis, Ioannis K. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Association for Cancer Research
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8898300/ https://www.ncbi.nlm.nih.gov/pubmed/34782370 http://dx.doi.org/10.1158/1541-7786.MCR-21-0266 |
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