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FAS receptor regulates NOTCH activity through ERK-JAG1 axis activation and controls oral cancer stemness ability and pulmonary metastasis

Pulmonary metastasis occurring via the colonization of circulating cancer stem cells is a major cause of oral squamous cell carcinoma (OSCC)-related death. Thus, understanding the mechanism of OSCC pulmonary metastasis may provide a new opportunity for OSCC treatment. FAS, a well-known apoptosis-ind...

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Detalles Bibliográficos
Autores principales: Li, Li-Jie, Chang, Peter Mu-Hsin, Li, Chien-Hsiu, Chang, Yu-Chan, Lai, Tsung-Ching, Su, Chia-Yi, Chen, Chi-Long, Chang, Wei-Min, Hsiao, Michael, Feng, Sheng-Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8898312/
https://www.ncbi.nlm.nih.gov/pubmed/35249111
http://dx.doi.org/10.1038/s41420-022-00899-5