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Identification of Gαi3 as a promising target for osteosarcoma treatment

Sustained activation of multiple receptor tyrosine kinases (RTKs) simultaneously is vital for tumorigenesis and progression of osteosarcoma (OS). Gαi proteins recruitment to various RTKs mediates downstream oncogenic signaling activation. The expression, functions and underlying mechanisms of Gαi3 i...

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Detalles Bibliográficos
Autores principales: Bian, Zheng-jun, Shan, Hua-jian, Zhu, Yun-Rong, Shi, Ce, Chen, Min-bin, Huang, Yu-min, Wang, Xiao-dong, Zhou, Xiao-zhong, Cao, Cong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8898352/
https://www.ncbi.nlm.nih.gov/pubmed/35280670
http://dx.doi.org/10.7150/ijbs.68861