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PrP(C) Promotes Endometriosis Progression by Reprogramming Cholesterol Metabolism and Estrogen Biosynthesis of Endometrial Stromal Cells through PPARα Pathway

Endometriosis (EMs) is characterized as an estrogen-dependent disease. Whereas, the underlying mechanism for activated estrogen biosynthesis in EMs lesions is largely unknown. We analyzed cholesterol metabolism and estrogen biosynthesis condition of EMs lesions by biological information analysis of...

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Detalles Bibliográficos
Autores principales: Peng, Hai-Yan, Lei, Sha-Ting, Hou, Shu-Hui, Weng, Li-Chun, Yuan, Qing, Li, Ming-Qing, Zhao, Dong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8898366/
https://www.ncbi.nlm.nih.gov/pubmed/35280685
http://dx.doi.org/10.7150/ijbs.68015