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TSG-6 promotes Cancer Cell aggressiveness in a CD44-Dependent Manner and Reprograms Normal Fibroblasts to create a Pro-metastatic Microenvironment in Colorectal Cancer

Tumor necrosis factor α stimulated gene 6 (TSG-6), a 30-KD secretory protein, plays an essential role in modulating inflammatory responses and extracellular matrix remodeling. However, little is known regarding the role of TSG-6 in human cancers. Here, we investigated the mechanism of action and the...

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Detalles Bibliográficos
Autores principales: Liu, Binbin, Liu, Tengfei, Liu, Yiting, Feng, Xingzhi, Jiang, Xuefei, Long, Jiahui, Ye, Shubiao, Chen, Daici, Wang, Jianping, Yang, Zihuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8898369/
https://www.ncbi.nlm.nih.gov/pubmed/35280699
http://dx.doi.org/10.7150/ijbs.69178