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Activation of AKT/mammalian target of rapamycin signaling in the peripheral blood of women with premature ovarian insufficiency and its correlation with FMR1 expression

BACKGROUND: The protein kinase B (AKT)/mammalian target of rapamycin (mTOR) signaling pathway regulates early follicular activation and follicular pool maintenance in female germline cells. Fragile X mental retardation 1 (FMR1) regulates folliculogenesis and it is variably expressed in patients with...

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Detalles Bibliográficos
Autores principales: Rehnitz, Julia, Messmer, Birgitta, Bender, Ulrike, Nguyen, Xuan Phuoc, Germeyer, Ariane, Hinderhofer, Katrin, Strowitzki, Thomas, Capp, Edison
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8898473/
https://www.ncbi.nlm.nih.gov/pubmed/35248053
http://dx.doi.org/10.1186/s12958-022-00919-0