In silico drug repositioning based on integrated drug targets and canonical correlation analysis

BACKGROUND: Besides binding to proteins, the most recent advances in pharmacogenomics indicate drugs can regulate the expression of non-coding RNAs (ncRNAs). The polypharmacological feature in drugs enables us to find new uses for existing drugs (namely drug repositioning). However, current computat...

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Detalles Bibliográficos
Autores principales: Chen, Hailin, Zhang, Zuping, Zhang, Jingpu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8898485/
https://www.ncbi.nlm.nih.gov/pubmed/35249529
http://dx.doi.org/10.1186/s12920-022-01203-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8898485/
https://www.ncbi.nlm.nih.gov/pubmed/35249529
http://dx.doi.org/10.1186/s12920-022-01203-1

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