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In silico drug repositioning based on integrated drug targets and canonical correlation analysis
BACKGROUND: Besides binding to proteins, the most recent advances in pharmacogenomics indicate drugs can regulate the expression of non-coding RNAs (ncRNAs). The polypharmacological feature in drugs enables us to find new uses for existing drugs (namely drug repositioning). However, current computat...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8898485/ https://www.ncbi.nlm.nih.gov/pubmed/35249529 http://dx.doi.org/10.1186/s12920-022-01203-1 |